On June 29, 2020 Eastern Time, The U.S. Securities and Exchange Commission (" SEC ") approved and declared effective the prospectus for the U.S. Initial public Offering of Zhong Yuan Bio-Technology Holdings Ltd.

This press release is not an offer to sell, nor is it seeking an offer to buy, these securities in any jurisdiction where the offer or sale is not permitted.

During the IPO, the Company will offer 2,000,000 to 4,000,000 shares of common stock. The offering will be conducted on an SEC registered prospectus only.